Until the entire continent is infected. Everything it touches grows ill and eventually dies. People, the land, the animals. The only way to stop a blight is to find the archdemon who started it and kill the bastard and even then... the land doesn't recover. Not quickly at least.
Seeing how you're more likely to die from infection or simply the sheer number of demons before finding the bastard? Incredibly difficult. Grey Wardens are usually the unlucky few who have the skill to do so but they've become increasingly rare.
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